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Cat No | BIOC1118 |
Conjugate | |
Source | N/A |
Size | 50 mg |
Application | Immunology |
Format | Powder |
Storage | Store at -20℃. |
Synonyms | EDC.HCl; N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride; 25952-53-8; EDAC; WSC; N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride; EDC hydrochloride; WSC hydrochloride; Carbodiimide; 偶联剂; N-乙基-N′-(3-二甲基氨丙基)碳二亚胺盐酸盐; EDC 盐酸盐; WSC 盐酸盐; 1-(3-二甲氨基丙基)-3-乙基碳二亚胺盐酸盐; 偶联剂 |
Purification | |
MolecularWeight | 191.7 |
Description | |
Background | 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually obtained as the hydrochloride. It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. Additionally, EDC can also be used to activate phosphate groups in order to form phosphomono-esters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation of immunoconjugates. EDC is often used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules. |