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Rabbit anti-Human NLRP6 Polyclonal Antibody

Cat NoBPA-5685
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size50 uL
ApplicationWB; IHC; IF; IP
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsNLRP6; AVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5
PurificationAffinity purification
MolecularWeight99KDa
Description
BackgroundThe protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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